FGF-8B (Animal Free) Human/Murine 25 µg

In stock

Cat-Nr.
100-020-AF
Size
25 µg
  €272.00

Description / FGF-8B (Animal Free)

FGF-8 (FGF-8b) is a heparin-binding growth factor belonging to the FGF family. Proteins of this family play a central role during prenatal development, postnatal growth and regeneration of a variety of tissues, by promoting cellular proliferation and differentiation. There are 4 known alternate spliced forms of FGF8; FGF-8A, FGF-8B, FGF-8E and FGF-8F. The human and murine FGF-8A and B are identical, unlike human and mouse FGF-8E and F, which are 98% identical. FGF-8 targets mammary carcinoma cells and other cells expressing the FGF receptors. Recombinant Human/Murine FGF-8 (FGF-8b) is a 22.5 kDa protein consisting of 194 amino acid residues.

More Information

Size 25 µg
Source E. coli
Biological Activity Determined by a cell proliferation assay using balb/c 3T3 cells. The expected ED50 for this effect is 2.0-4.0 ng/ml.
Purity Confirmation ≥ 97% by SDS-PAGE gel and HPLC analyses.
Length [aa] 193
Molecular Weight 22.4 kDa
Formulation lyophilized
Protein Sequence MQVTVQSSPN FTQHVREQSL VTDQLSRRLI RTYQLYSRTS GKHVQVLANK RINAMAEDGD PFAKLIVETD TFGSRVRVRG AETGLYICMN KKGKLIAKSN GKGKDCVFTE IVLENNYTAL QNAKYEGWYM AFTRKGRPRK GSKTRQHQRE VHFMKRLPRG HHTTEQSLRF EFLNYPPFTR SLRGSQRTWA PEPR
Synonyms FGF8; AIGF; KAL6; FGF-8; HBGF-8
Uniprot ID P55075
Protein RefSeq NP_149355
mRNA RefSeq NM_033165
Pluripotent stem cells-derived organoids Cortical

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