FGF-8a Human 5 µg

In stock

Cat-Nr.
100-438S
Size
5 µg
  €112.00

Description / FGF-8a

FGF-8 is a heparin-binding growth factor belonging to the FGF family. Proteins of this family play a central role during prenatal development, postnatal growth and regeneration of a variety of tissues, by promoting cellular proliferation and differentiation. There are 4 known alternate spliced forms of FGF8; FGF-8a, FGF-8b, FGF-8e and FGF-8f. The human and murine FGF-8a and FGF-8b are identical, unlike human and mouse FGF-8e and FGF-8f, which are 98% identical. FGF-8 targets mammary carcinoma cells and other cells expressing the FGF receptors. CHO cell-derived recombinant human FGF-8a is a 21.2 kDa protein consisting of 182 amino acid residues.

More Information

Size 5 µg
Source CHO cells
Biological Activity Determined by a cell proliferation assay using balb/c 3T3 cells.
Purity Confirmation > 95% by SDS-PAGE & HPLC analyses
Length [aa] 182
Molecular Weight 21.2 kDa
Species Reactivity Human
Formulation lyophilized
Protein Sequence QHVREQSLVT DQLSRRLIRT YQLYSRTSGK HVQVLANKRI NAMAEDGDPF AKLIVETDTF GSRVRVRGAE TGLYICMNKK GKLIAKSNGK GKDCVFTEIV LENNYTALQN AKYEGWYMAF TRKGRPRKGS KTRQHQREVH FMKRLPRGHH TTEQSLRFEF LNYPPFTRSL RGSQRTWAPE PR
Synonyms Fibroblast Growth Factor-8, FGF-8a, AIGF, HBGF-8
Uniprot ID P55075-2
Protein RefSeq NP_149355.1
mRNA RefSeq NM_033165.3
Pluripotent stem cells-derived organoids Cortical

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