Description / human FGF-7/KGF protein
Keratinocyte Growth Factor (KGF/FGF-7) is one of 23 known members of the FGF family. Proteins of this family play a central role during prenatal development and postnatal growth and regeneration of variety of tissues, by promoting cellular proliferation and differentiation. KGF/FG-7 is a mitogen factor specific for epithelial cells and keratinocytes and signals through FGFR 2b. KGF/FGF-7 plays a role in kidney and lung development, angiogenesis, and wound healing. Recombinant human KGF/FGF-7 is an 18.9 kDa protein consisting of 163 amino acid residues.
More Information
| Size | 500 µg |
|---|---|
| Source | E. coli |
| Biological Activity | The expected ED50 as determined by a cell proliferation assay using 4MBr-5 cells is 0.1-15 ng/ml. |
| Purity Confirmation | > 95% by SDS-PAGE & HPLC analyses |
| Length [aa] | 163 |
| Molecular Weight | 18.9 kDa |
| Species Reactivity | Mouse, Rat, Human, Leech |
| Formulation | lyophilized |
| Buffer | 15mM Sodium Phosphate, pH 7.0 + 25mM NaCl |
| Protein Sequence | CNDMTPEQMA TNVNCSSPER HTRSYDYMEG GDIRVRRLFC RTQWYLRIDK RGKVKGTQEM KNNYNIMEIR TVAVGIVAIK GVESEFYLAM NKEGKLYAKK ECNEDCNFKE LILENHYNTY ASAKWTHNGG EMFVALNQKG IPVRGKKTKK EQKTAHFLPM AIT |
| Reconstitution | Centrifuge the vial prior to opening. Reconstitute in sterile water to a concentration of 0.1-1.0 mg/ml. Do not vortex. This solution can be stored at 2-8°C for up to 1 week. For extended storage, it is recommended to further dilute in a buffer containing |
| Stability and Storage | The lyophilized protein is stable at room temperature for 3 weeks should be stored desiccated below -18°C. Reconstituted working aliquots are stable for 1 week at 2°C to 8°C and for 3 months at -20°C to -80°C. |
| Synonyms | KGF |
| Uniprot ID | P21781 |
| Protein RefSeq | NP_002000 |
| mRNA RefSeq | NM_002009 |
| Adult stem cells-derived organoids | Mammary, Urothelium |
| Pluripotent stem cells-derived organoids | Esophagus, Liver |