FGF-6 Human 5 µg

In stock

Cat-Nr.
100-019S
Size
5 µg
  €112.00

Description / FGF-6

FGF-6 is a secreted heparin binding growth factor that is a member of the FGF family. Proteins of this family play a central role during prenatal development and postnatal growth and regeneration of a variety of tissues, by promoting cellular proliferation and differentiation. FGF-6 is expressed in leukemia cell lines with platelet megakaryocytic differentiation potential. It signals through FGFR 1c, 2c, and 4. Recombinant human FGF-6 is an 18.7 kDa protein consisting of 168 amino acid residues.

More Information

Size 5 µg
Source E. coli
Biological Activity The ED50 as determined by the dose-dependent stimulation of thymidine uptake by BaF3 cells expressing FGF-receptors is ≤ 0.5 ng/ml, corresponding to a specific activity of ≥ 2 x 106 units/mg.
Purity Confirmation > 95% by SDS-PAGE & HPLC analyses
Length [aa] 168
Molecular Weight 18.7 kDa
Species Reactivity Human
Formulation lyophilized
Buffer 10 mM NaP, pH 7.2 + 50 mM NaCl
Protein Sequence GTRANNTLL DSRGWGTLLS RSRAGLAGEI AGVNWESGYL VGIKRQRRLY CNVGIGFHLQ VLPDGRISGT HEENPYSLLE ISTVERGVVS LFGVRSALFV AMNSKGRLYA TPSFQEECKF RETLLPNNYN AYESDLYQGT YIALSKYGRV KRGSKVSPIM TVTHFLPRI
Synonyms FGF6; HST2; HBGF-6
Uniprot ID P10767
Protein RefSeq NP_066276
mRNA RefSeq NM_020996

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