FGF-23 Anti-Human 100 µg

In stock

Cat-Nr.
102-P109
Size
100 µg
  €271.00

Description / FGF-23

The FGF family plays a central role during prenatal development and postnatal growth and regeneration of a variety of tissues, by promoting cellular proliferation and differentiation. FGF-23, FGF-21 and FGF-19 constitute an atypical FGF subfamily whose ligands act as circulating hormones and require the participation of a Klotho protein as a co-receptor for their signaling. FGF-23 is a bone-derived hormone that acts in the kidney to regulate phosphate homeostasis and vitamin D metabolism. The signaling receptor for FGF-23, a Klotho-FGFR1 (IIIc) complex, is an essential regulator of the renal sodium phosphate co-transporter and key vitamin D-metabolizing enzymes CYP27B1 and CYP24A1.

More Information

Size 100 µg
Source Rabbit
Clone Nr. Rabbit IgG
Species Reactivity Human
Formulation lyophilized
Buffer PBS
Preparation Produced from sera of rabbits immunized with highly pure Recombinant Human FGF-23. Anti-Human FGF-23-specific antibody was purified by affinity chromatography employing an immobilized Human FGF-23 matrix.
Antigen Recombinant human FGF-23
Application ELISA, WB
Synonyms FGF23; ADHR; HYPF; HPDR2; PHPTC ; fgf 23
Uniprot ID Q9GZV9
Protein RefSeq NP_065689.1
mRNA RefSeq NM_020638

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