Description / FGF-21
FGF-21 is a secreted growth factor that is a member of the FGF family. Proteins of this family play a central role during prenatal development, postnatal growth and regeneration of a variety of tissues, by promoting cellular proliferation and differentiation. FGF-21, in the presence of β-Klotho as a protein cofactor, signals through the FGFR 1c and 4 receptors, and stimulates insulin-independent glucose uptake by adipocytes. Recombinant Murine FGF-21 is a 20.1 kDa protein containing 182 amino acid residues.
More Information
Size | 5 µg |
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Source | E. coli |
Biological Activity | Determined by its ability to stimulate the proliferation of murine NIH-3T3 cells. |
Purity Confirmation | ≥ 95% by SDS-PAGE gel and HPLC analyses |
Length [aa] | 182 |
Molecular Weight | 20.1 kDa |
Species Reactivity | Mouse |
Formulation | lyophilized |
Protein Sequence | MAYPIPDSSP LLQFGGQVRQ RYLYTDDDQD TEAHLEIRED GTVVGAAHRS PESLLELKAL KPGVIQILGV KASRFLCQQP DGALYGSPHF DPEACSFREL LLEDGYNVYQ SEAHGLPLRL PQKDSPNQDA TSWGPVRFLP MPGLLHEPQD QAGFLPPEPP DVGSSDPLSM VEPLQGRSPS YAS |
Synonyms | Fibroblast Growth Factor-21, FGFL |
Uniprot ID | Q9JJN1 |
Protein RefSeq | NP_064397.1 |
mRNA RefSeq | NM_020013.4 |