FGF-21 Human 5 µg

In stock

Cat-Nr.
100-337S
Size
5 µg
  €112.00

Description / FGF-21

FGF-21 is a secreted growth factor that is a member of the FGF family. Proteins of this family play a central role during prenatal development and postnatal growth and regeneration of a variety of tissues, by promoting cellular proliferation and differentiation. FGF-21, in the presence of betaKlotho as a protein cofactor, signals through the FGFR 1c and 4 receptors and stimulates insulin independent glucose uptake by adipocytes. Recombinant human FGF-21 is a 19.5 kDa protein containing 182 amino acid residues.

More Information

Size 5 µg
Source E. coli
Biological Activity FGF-21, in the absence of betaKlotho, shows weak activity of thymidine uptake by BaF3 cells expressing FGF receptors.
Purity Confirmation > 90% by SDS-PAGE & HPLC analyses
Length [aa] 182
Molecular Weight 19.5 kDa
Species Reactivity Human
Formulation lyophilized
Protein Sequence MHPIPDSSPL LQFGGQVRQR YLYTDDAQQT EAHLEIREDG TVGGAADQSP ESLLQLKALK PGVIQILGVK TSRFLCQRPD GALYGSLHFD PEACSFRELL LEDGYNVYQS EAHGLPLHLP GNKSPHRDPA PRGPARFLPL PGLPPALPEP PGILAPQPPD VGSSDPLSMV GPSQGRSPSY AS
Synonyms FGF21
Uniprot ID Q9NSA1
Protein RefSeq NP_061986.1
mRNA RefSeq NM_019113

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