Description / human FGF-20 protein
FGF-20 is secreted heparin binding growth factor that is a member of the FGF family. Proteins of this family play a central role during prenatal development and postnatal growth and regeneration of a variety of tissues, by promoting cellular proliferation and differentiation. FGF-20 signals through the FGFR 2c and 3c and is expressed during limb and brain development. Recombinant human FGF-20 is a 23.2 kDa protein containing 209 amino acid residues.
More Information
| Size | 250 µg |
|---|---|
| Source | E. coli |
| Biological Activity | The ED50 as determined by the dose-dependent stimulation of thymidine uptake by BaF3 cells expressing FGF-receptors is ≤ 10 ng/ml, corresponding to a specific activity of ≥ 1 x 105 units/mg. |
| Purity Confirmation | > 90% by SDS-PAGE & HPLC analyses |
| Length [aa] | 209 |
| Molecular Weight | 23.2 kDa |
| Species Reactivity | Monkey, Mouse |
| Formulation | lyophilized |
| Buffer | 25mM Tris, pH 7.6 + 1.5M NaCl |
| Protein Sequence | PLAEVGGFLG GLEGLGQQVG SHFLLPPAGE RPPLLGERRS AAERSARGGP GAAQLAHLHG ILRRRQLYCR TGFHLQILPD GSVQGTRQDH SLFGILEFIS VAVGLVSIRG VDSGLYLGMN DKGELYGSEK LTSECIFREQ FEENWYNTYS SNIYKHGDTG RRYFVALNKD GTPRDGARSK RHQKFTHFLP RPVDPERVPE LYKDLLMYT |
| Reconstitution | Reconstitute in 10mM Tris, pH 7.6, to a concentration of 0.1-1.0 mg/ml |
| Synonyms | FGF20; FGF-20 |
| Uniprot ID | Q9NP95 |
| Protein RefSeq | NP_062825.1 |
| mRNA RefSeq | NM_019851 |