Description / FGF-19
The FGF family plays central roles during prenatal development and postnatal growth and regeneration of a variety of tissues, by promoting cellular proliferation and differentiation. FGF-19, a member of the FGF family, is a high affinity heparin dependent ligand for FGFR4. FGF-19 is expressed during the brain development and embryogenesis. Recombinant human FGF-19 is a 21.8 kDa protein containing 195 amino acid residues.
More Information
Size | 5 µg |
---|---|
Source | E. coli |
Biological Activity | Determined by a cell proliferation assay using balb/c 3T3 cells. The expected ED50 for this effect is 100-150 ng/ml. |
Purity Confirmation | > 95% by SDS-PAGE & HPLC analyses |
Length [aa] | 195 |
Molecular Weight | 21.8 kDa |
Species Reactivity | Mouse, Hamster |
Formulation | lyophilized |
Protein Sequence | MRPLAFSDAG PHVHYGWGDP IRLRHLYTSG PHGLSSCFLR IRADGVVDCA RGQSAHSLLE IKAVALRTVA IKGVHSVRYL CMGADGKMQG LLQYSEEDCA FEEEIRPDGY NVYRSEKHRL PVSLSSAKQR QLYKNRGFLP LSHFLPMLPM VPEEPEDLRG HLESDMFSSP LETDSMDPFG LVTGLEAVRS PSFEK |
Synonyms | FGF19 |
Uniprot ID | O95750 |
Protein RefSeq | NP_005108.1 |
mRNA RefSeq | NM_005117 |
Pluripotent stem cells-derived organoids | Liver |