FGF-18 (Animal Free) Human 5 µg

In stock

Cat-Nr.
100-025S-AF
Size
5 µg
  €139.00

Description / FGF-18 (Animal Free)

FGF-18 is a heparin-binding growth factor that belongs to the FGF family. Proteins of this family play a central role during prenatal development, postnatal growth and regeneration of a variety of tissues, by promoting cellular proliferation and differentiation. FGF-18 is an essential regulator of long bone and calvarial development. FGF-18 signals through FGFR 1c, 2c, 3c, and 4. Recombinant Human FGF-18 derived from E.coli is a 20.1 kDa protein consisting of 173 amino acid residues, resulting from C-terminal truncation of the full length protein.

More Information

Size 5 µg
Source E. coli
Biological Activity Determined by a cell proliferation assay using Balb/c 3T3 cells. The expected ED50 is ≤ 10 ng/ml, corresponding to a specific activity of ≥ 1 x 105 units/mg.
Purity Confirmation ≥ 95% by SDS-PAGE gel and HPLC analyses.
Length [aa] 173
Molecular Weight 20.1 kDa
Species Reactivity Mouse, Rat, Human
Formulation lyophilized
Protein Sequence AEENVDFRIH VENQTRARDD VSRKQLRLYQ LYSRTSGKHI QVLGRRISAR GEDGDKYAQL LVETDTFGSQ VRIKGKETEF YLCMNRKGKL VGKPDGTSKE CVFIEKVLEN NYTALMSAKY SGWYVGFTKK GRPRKGPKTR ENQQDVHFMK RYPKGQPELQ KPFKYTTVTK RSR
Synonyms FGF18; ZFGF5; FGF-18
Uniprot ID O76093
Protein RefSeq NP_003853.1
mRNA RefSeq NM_003862

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