Description / human FGF-17 protein
FGF-17 is a heparin binding growth factor that is a member of the FGF family. Proteins of this family play a central role during prenatal development and postnatal growth and regeneration of a variety of tissues, by promoting cellular proliferation and differentiation. FGF-17 signals through the FGFR 1c, 2c, 3c, and 4. FGF-17 signals induction and patterning of embryonic brain. Recombinant human FGF-17 is a 22.7 kDa protein consisting of 195 amino acid residues.
More Information
| Size | 250 µg |
|---|---|
| Source | E. coli |
| Biological Activity | Assay #1: The ED50 as determined by the dose-dependent stimulation of thymidine uptake by BaF3 cells expressing FGF-receptors is ≤ 0.5 ng/ml (≥ 2 x 106 units/mg. Assay #2: The ED50 was determined by a cell proliferation assay using balb/c 3T3 cells is ≤ 1 |
| Purity Confirmation | > 95% by SDS-PAGE & HPLC analyses |
| Length [aa] | 195 |
| Molecular Weight | 22.7 kDa |
| Species Reactivity | Mouse |
| Formulation | lyophilized |
| Protein Sequence | MTQGENHPSP NFNQYVRDQG AMTDQLSRRQ IREYQLYSRT SGKHVQVTGR RISATAEDGN KFAKLIVETD TFGSRVRIKG AESEKYICMN KRGKLIGKPS GKSKDCVFTE IVLENNYTAF QNARHEGWFM AFTRQGRPRQ ASRSRQNQRE AHFIKRLYQG QLPFPNHAEK QKQFEFVGSA PTRRTKRTRR PQPLT |
| Synonyms | FGF17; FGF-13 |
| Uniprot ID | O60258 |
| Protein RefSeq | NP_003858 |
| mRNA RefSeq | NM_003867 |