Eotaxin-3 Anti-Human 500 µg

In stock

Cat-Nr.
101-M19
Size
500 µg
  €221.00

Description / Eotaxin-3

Eotaxin3, also named CCL26 or SCYA26, is a novel human CC chemokine that maps to chromosome 7q11.2, within 40 kilobases of the Eotaxin2 loci. Eotaxin3/ CCL26 has been shown to be constitutively expressed in the heart and ovary. In addition, low levels of Eotaxin3/ CCL26 expression can also be detected in various tissues. The expression of Eotaxin 3/CCL26 in vascular endothelial cells has been shown to be upregulated by IL13 and IL4. Eotaxin3/ CCL26 cDNA encodes a 94 amino acid (aa) residue protein with a putative signal peptide of either 23 or 26 aa residues. Eotaxin3/ CCL26 induces calcium flux in eosinophils as well as in CCR3transfected cells. Eotaxin 3/ CCL26 has also been shown to cross-desensitize cells to other CCR3 ligands.

More Information

Size 500 µg
Source Mouse
Isotype IgG1, kappa
Species Reactivity Human
Formulation lyophilized from PBS
Buffer PBS
Reconstitution Centrifuge vial prior to opening. Reconstitute in sterile water to a concentration of 0.1-1.0 mg/ml.
Stability and Storage The lyophilized antibody is stable for at least 2 years from date of receipt at -20°C. The reconstituted antibody is stable for at least two weeks at 2-8°C. Frozen aliquots are stable for at least 6 months when stored at -20°C.
Preparation Produced in BALB/c mice using recombinant hEotaxin-3 as the immunizing antigen. IgG1/K antibody was purified from ascites fluid on a Protein A affinity column.
Antigen Recombinant Human Eotaxin-3 (CCL26)
Application ELISA, WB, N
Synonyms CCL26; IMAC; TSC-1; MIP-4a; SCYA26; MIP-4alpha
Uniprot ID Q9Y258
Protein RefSeq NP_006063
mRNA RefSeq NM_006072

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