E-Cadherin Anti-Mouse 100 µg

In stock

Cat-Nr.
103-M523
Size
100 µg
  €533.00

Description / E-Cadherin

E-Cadherin/Cadherin1, also known as Uvomorulin in the mouse and rat, is a 120 kDa member of the Cadherin family of cell surface glycoproteins that mediate cell adhesion. Mouse ECadherin shares 92% and 81% amino acid sequence identity with the rat and human proteins, respectively. It is a single-pass transmembrane protein that mediates calcium-dependent epithelial cell adhesion. E-Cadherin has five extracellular EC domains that form homophilic cis-clusters between adjacent epithelial cells and trans-clusters within the same cell. E-Cadherin clusters are critical components of adherens junctions between epithelial cells and act in the formation and maintenance of the epithelial cell barrier.

More Information

Size 100 µg
Source Rat
Isotype IgG1
Clone Nr. (#6N32)
Formulation lyophilized
Buffer PBS
Reconstitution Centrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.
Stability and Storage Lyophilized samples are stable for 2 years from date of receipt when stored at -70°C. Reconstituted antibody can be aliquoted and stored frozen at < -20°C for at least six months without detectable loss of activity.
Antigen Mouse recombinant protein E-cadherin
Application E
Synonyms Cadherin-1; ARC-1, Epithelial cadherin (E-cadherin), Uvomorulin
Uniprot ID P09803
Protein RefSeq NP_033994.1.
mRNA RefSeq NM_009864.3

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