Description / anti-human Cystatin C monoclonal antibody
Cystatin C is a member of family 2 of the cystatin superfamily. It inhibits many cysteine proteases such as papain and Cathepsins B, H, K, L and S. It is ubiquitous in human tissues and body fluids. A point mutation in the gene coding for the 120 amino acid mature Cystatin C causes a hereditary form of amyloid angiopathy in which the protein variant (Leu 68 to Gln) is deposited in the cerebral arteries, leading to fatal cerebral hemorrhage.
More Information
| Size | 100 µg |
|---|---|
| Source | Mouse |
| Isotype | IgG2 |
| Clone Nr. | (#3N77) |
| Species Reactivity | Human |
| Formulation | lyophilized |
| Buffer | PBS |
| Reconstitution | Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml. |
| Stability and Storage | Lyophilized samples are stable for 2 years from date of receipt when stored at -70°C. Reconstituted antibody can be aliquoted and stored frozen at < -20 °C for at least for six months without detectable loss of activity. |
| Preparation | This antibody was produced from a hybridoma (mouse myeloma fused with spleen cells from a mouse) immunized with human recombinant Cystatin-C. |
| Antigen | human recombinant Cystatin C |
| Application | IHC, Capture Ab |
| Synonyms | CST3; ARMD11 |
| Uniprot ID | P01034 |
| Protein RefSeq | NP_000090.1 |
| mRNA RefSeq | NM_000099.2 |