Description / Anti-Human CXCL9 (MIG) monoclonal antibody
MIG or CXCL9 , a CXC chemokine, is produced by IFN stimulated monocytes, macrophages and endothelial cells. It signals through the CXCR3 receptor. MIG selectively chemoattracts Th1 lymphocytes, and also exerts other activities including inhibition of tumor growth, angiogenesis, and inhibition of colony formation of hematopoietic progenitors. Human MIG is active on murine cells. Recombinant human MIG is an 11.7 kDa protein containing 103 amino acid residues, including the four highly conserved cysteine residues present in CXC chemokines.
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| Size | 50 µg |
|---|---|
| Source | Mouse |
| Isotype | IgG1 |
| Biological Activity | IHC (frozen) 1:20-100; FC 1:50-200; WB 1:500-1000; Neutralization of CXCL9 mediated bioreactivity |
| Clone Nr. | (#7F11) |
| Species Reactivity | Human |
| Formulation | lyophilized |
| Buffer | PBS |
| Reconstitution | Centrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml. |
| Stability and Storage | Lyophilized samples are stable for 2 years from date of receipt when stored at -70°C. Reconstituted antibody can be aliquoted and stored frozen at < -20°C for at least six months without detectable loss of activity. |
| Preparation | This antibody was produced from a hybridoma (mouse myeloma fused with spleen cells from a mouse immunized with human recombinant CXCL9 (also called MIG). The IgG fraction of culture supernatant was purified by Protein G affinity chromatography and lyophil |
| Antigen | recombinant human CXCL-9 |
| Application | WB, IHC (F), FC, N |
| Synonyms | C-X-C motif chemokine 9; CXCL9; CMK; MIG; HuMIG; SCYB9; crg-10; Small-inducible cytokine B9; Monokine induced by interferon-gamma |
| Uniprot ID | Q07325 |
| Protein RefSeq | NP_002407.1 |
| mRNA RefSeq | NM_002416.1. |