Description / Chemerin
Chemerin, also known as retinoic acid receptor responder protein 2 (RARRES2), tazarotene-induced gene 2 protein (TIG2), or RAR-responsive protein TIG2 is a protein that in humans is encoded by the RARRES2 gene. Chemerin is a chemoattractant protein that acts as a ligand for the G protein-coupled receptor CMKLR1 (also known as ChemR23). Chemerin is a 14 kDa protein secreted in an inactive form as prochemerin and is activated through cleavage of the C-terminus by inflammatory and coagulation serine proteases. Chemerin was found to stimulate chemotaxis of dendritic cells and macrophages to the site of inflammation.
More Information
Size | 100 µg |
---|---|
Source | Rat |
Isotype | IgG2 |
Clone Nr. | (#13G2) |
Antigen | Mouse recombinant Chemerin |
Application | E |
Synonyms | Retinoic acid receptor responder protein 2, Rarres2 |
Uniprot ID | Q9DD06 |
Protein RefSeq | NP_001334097.1 |
mRNA RefSeq | NM_001347168.1 |