Cerberus-1 Anti-Human 100 µg

In stock

Cat-Nr.
101-M321
Size
100 µg
  €533.00

Description / Cerberus-1

Cerberus 1, also called DAND4, is a member of the DAN domain family of BMP antagonists that includes DAN (DAND1), Gremlin/Drm (DAND2), PRDC (Protein Related to Dan and Cerberus; DAND3), and COCO/Dante (DAND5). DAN family members contain a cysteine knot domain that is homologous to that found in other TGF-beta superfamily ligands. Cerberus 1 is a secreted glycoprotein that forms disulfide-linked homodimers. Cerberus-S, which is generated by proteolysis in Xenopus, is a short version of the molecule and includes the C-terminal cysteine knot domain.

More Information

Size 100 µg
Source Mouse
Isotype IgG2
Clone Nr. (#4K48)
Species Reactivity Human
Formulation lyophilized
Buffer PBS
Reconstitution Centrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.
Stability and Storage Lyophilized samples are stable for 2 years from date of receipt when stored at -70°C. Reconstituted antibody can be aliquoted and stored frozen at < -20°C for at least six months without detectable loss of activity.
Preparation This antibody was produced from a hybridoma (mouse myeloma fused with spleen cells from a mouse) immunized with human recombinant protein of Cerberus-1.
Antigen human recombinant Cerberus-1
Application WB, IHC (P)
Synonyms CER1; DAND4
Uniprot ID O95813
Protein RefSeq NP_005445.1
mRNA RefSeq NM_005454.2

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