Description / CEACAM-1
Carcinoembryonic Antigen-related Cell Adhesion Molecule 1 (CEACAM-1), also known as CD66a and BGP-I, is a 115 kDa type I transmembrane glycoprotein that belongs to the membrane-bound CEA subfamily of the CEA superfamily. On the surface of cells, it forms noncovalent homo- and heterodimers. The extracellular region contains three C2-type Ig-like domains and one N-terminal V-type Ig-like domain. Multiple splice variants involving regions C-terminal to the second C2-type domain (aa 320 and beyond) exist.
More Information
Size | 100 µg |
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Source | Mouse |
Isotype | IgG1, kappa |
Biological Activity | ELISA: Use at 10 µg/ml; WB: Use at 10 µg/ml; Immunohistochemistry: Use at 10 µg/ml; FACS analysis: Use at 10 µg/ml. |
Clone Nr. | (#C5-1X) |
Species Reactivity | Human |
Formulation | lyophilized |
Buffer | PBS |
Reconstitution | Centrifuge vial prior to opening. Reconstitute in sterile water to a concentration of 0.1-1.0 mg/ml. |
Stability and Storage | The lyophilized antibody is stable for at least 2 years at -20°C. After sterile reconstitution the antibody is stable at 2-8°C for up to 6 months. Frozen aliquots are stable for at least 6 months when stored at -20°C. Addition of a carrier protein or 50% |
Preparation | Monoclonal antibodies were produced with the help of BALB/c mice using recombinant human soluble CEACAM-1-Fc (produced in HEK293 cells) as the immunizing antigen. Mouse IgG1kappa antibody (clone #C5-1X) was purified from cell culture supernatant by Protei |
Antigen | recombinant human soluble CEACAM-1-Fc (produced in HEK293 cells) |
Application | WB, IHC, E, IF, IP, FC |
Synonyms | CEACAM1; BGP; BGP1; BGPI, CD66a |
Uniprot ID | P13688 |
Protein RefSeq | NP_001192273.1 |
mRNA RefSeq | NM_001205344.1 |