Description / anti-mouse CD86 monoclonal antibody
CD86 is an 80 kD immunoglobulin superfamily member, also known as B7-2, B70, and Ly-58. CD86 is expressed on activated B and T cells, macrophages, dendritic cells and astrocytes. CD86 binds to CD28 to transduce co-stimulatory signals for T cell activation, proliferation, and cytokine production.
More Information
| Size | 100 µg |
|---|---|
| Source | Rat |
| Isotype | IgG2 |
| Clone Nr. | (#MAB0803) |
| Species Reactivity | Mouse |
| Formulation | lyophilized |
| Buffer | PBS |
| Reconstitution | Centrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml. |
| Stability and Storage | Lyophilized samples are stable for 2 years from date of receipt when stored at -70°C. Reconstituted antibody can be aliquoted and stored frozen at < -20°C for at least six months without detectable loss of activity. |
| Preparation | This antibody was produced from a hybridoma (mouse myeloma fused with spleen cells from a rat) immunized with LPS stimulated mouse B-cells. IgG2 fraction of the culture supernatant was purified by Protein G affinity chromatography. |
| Antigen | LPS stimulated Mouse B-Cells |
| Application | IHC (P), FC, IP |
| Synonyms | B7-2; B70; Ly-58 |
| Uniprot ID | P42082 |
| Protein RefSeq | NP_062261.3 |
| mRNA RefSeq | NM_019388.3 |