Description / CD40
CD40 plays a key role in B-cell growth and differentiation where interactions of CD40 with its ligand, CD154, are involved in the initiation, effector, and memory stages of cell-mediated immune responses. In addition, CD40 has been reported to be involved with the triggering of NK cells and NK-T cells.
More Information
Size | 100 µg |
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Source | Rat |
Isotype | IgG2 |
Clone Nr. | (#MAB0805) |
Species Reactivity | Mouse |
Formulation | lyophilized |
Buffer | PBS |
Reconstitution | Centrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml. |
Stability and Storage | Lyophilized samples are stable for 2 years from date of receipt when stored at -70°C. Reconstituted antibody can be aliquoted and stored frozen at < -20°C for at least six months without detectable loss of activity. |
Preparation | This antibody was produced from a hybridoma (mouse myeloma fused with spleen cells from a rat immunized with recombinant mouse CD40 protein. IgG2 fraction of the culture supernatant was purified by Protein G affinity chromatography. |
Antigen | Mouse recombinant CD40 |
Application | IHC (P) |
Synonyms | Cd40; IGM; p50; Bp50; GP39; IMD3; TRAP; HIGM1; T-BAM; Tnfrsf5; AI326936 |
Uniprot ID | P27512 |
Protein RefSeq | NP_035741.2 |
mRNA RefSeq | NM_011611.2 |