Description / Anti-Human CD40 monoclonal antibody
CD40 is a type I transmembrane glycoprotein belonging to the TNF receptor superfamily. CD40 is expressed on B cells, follicular dendritic cells, dendritic cells, activated monocytes, macrophages, endothelial cells, vascular smooth muscle cells and several tumor cell lines.
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| Size | 50 µg |
|---|---|
| Source | Mouse |
| Isotype | IgG2 |
| Clone Nr. | (#9F21) |
| Species Reactivity | Human |
| Formulation | lyophilized |
| Buffer | PBS |
| Reconstitution | Centrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml. |
| Stability and Storage | Lyophilized samples are stable for 2 years from date of receipt when stored at -70°C. Reconstituted antibody can be aliquoted and stored frozen at < -20°C for at least six months without detectable loss of activity. |
| Preparation | This antibody was produced from a hybridoma (mouse myeloma fused with spleen cells from a mouse immunized with recombinant human CD40 extra cellular domain. IgG2 fraction of culture supernatant was purified by Protein G affinity chromatography. |
| Antigen | human recombinant CD40 extra cellular domain |
| Application | ELISA, WB, IHC, FC |
| Synonyms | CD40; p50; Bp50; CDW40; TNFRSF5 |
| Uniprot ID | P25942 |
| Protein RefSeq | NP_001241.1 |
| mRNA RefSeq | NM_001250.4 |