Description / Anti-Mouse CD36 monoclonal antibody
CD36, also known as scavenger receptor class B member 3 (SR-B3), platelet membrane glycoprotein IV (GPIV), GPIIIb, thrombospondin receptor, collagen receptor, and fatty acid translocase (FAT), is a broadly-expressed integral membrane glycoprotein that has multiple physiological functions. As a member of the scavenger receptor family, CD36 is a multi-ligand pattern recognition receptor that interacts with a large number of structurally dissimilar ligands. Upon ligand binding, CD36 transduces signals that mediate a wide range of pro-inflammatory cellular responses.
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| Size | 50 µg |
|---|---|
| Source | Mouse |
| Isotype | IgG1 |
| Biological Activity | IHC(F): 1:50-200 |
| Clone Nr. | (#11R8) |
| Species Reactivity | Mouse |
| Formulation | lyophilized |
| Buffer | PBS |
| Reconstitution | Centrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml. |
| Stability and Storage | Lyophilized samples are stable for 2 years from date of receipt when stored at -70°C. Reconstituted antibody can be aliquoted and stored frozen at < -20°C for at least six months without detectable loss of activity. |
| Preparation | This antibody was produced from a hybridoma (mouse myeloma fused with spleen cells from a rat immunized with recombinant mouse CD36 (also called GPIV, thrombospondin receptor, FAT, and SR-B3), which is an 88 kDa, integral membrane glycoprotein that belong |
| Antigen | Recombinant mouse CD36 |
| Application | IHC (F), FC |
| Synonyms | CD36; FAT; GP4; GP3B; GPIV; CHDS7; PASIV; SCARB3; BDPLT10 |
| Uniprot ID | Q08857 |
| Protein RefSeq | NP_031669.3. |
| mRNA RefSeq | NM_007643.4 |