Description / anti-human CD102 monoclonal antibody
Intercellular adhesion molecule 2 (ICAM-2), also known as CD102, is a member of the immunoglobulin superfamily and binds the leukocyte integrins LFA-1 (CD11a/CD18) and Mac-1 (CD11b/CD18). ICAM-2 is constitutively expressed at high levels on vascular endothelial cells and lymphohematopoietic cells. ICAM-2 mediated adhesion has been shown to provide a co-stimulatory signal for T cell aggregation, NK cytotoxicity and NK cell migration.
More Information
| Size | 100 µg |
|---|---|
| Source | Mouse |
| Isotype | IgG1 |
| Clone Nr. | (#7L4) |
| Species Reactivity | Human |
| Formulation | lyophilized |
| Buffer | PBS |
| Reconstitution | Centrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml. |
| Stability and Storage | Lyophilized samples are stable for 2 years from date of receipt when stored at -70°C. Reconstituted antibody can be aliquoted and stored frozen at < -20°C for at least six months without detectable loss of activity. |
| Preparation | This antibody was produced from a hybridoma (mouse myeloma fused with spleen cells from a mouse) immunized with human recombinant protein of CD102 extracellular domain (also called ICAM-2). |
| Antigen | Human recombinant CD102 EC domain |
| Application | WB |
| Synonyms | ICAM2; CD102 |
| Uniprot ID | P13598 |
| Protein RefSeq | NP_001093256.1 |
| mRNA RefSeq | NM_001099786.1 |