Description / anti-human Cathepsin V monoclonal antibody
Cathepsin V (also known as Cathepsin L2 and U) is a cysteine protease of the papain family. It is expressed as a proenzyme in lysosomes, which can be autocatalytically converted to the mature form at pH 4.0. Cathepsin V shows high amino acid identity with Cathepsin L (77% for the proenzymes and 80% for the mature enzymes). However, Cathepsin V is specifically expressed in the thymus, testis, and corneal epithelium whereas Cathepsin L is expressed throughout the body.
More Information
| Size | 100 µg |
|---|---|
| Source | Mouse |
| Isotype | IgG1 |
| Clone Nr. | (#9G24) |
| Species Reactivity | Human |
| Formulation | lyophilized |
| Buffer | PBS |
| Reconstitution | Centrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml. |
| Stability and Storage | Lyophilized samples are stable for 2 years from date of receipt when stored at -70°C. Reconstituted antibody can be aliquoted and stored frozen at < -20°C for at least six months without detectable loss of activity. |
| Preparation | This antibody was produced from a hybridoma (mouse myeloma fused with spleen cells from a mouse) immunized with human recombinant protein of Cathepsin-V. |
| Antigen | recombinant human Cathepsin-V |
| Application | WB, IHC (P) |
| Synonyms | CTSL2; CTSU; CTSV; CATL2 |
| Uniprot ID | O60911 |
| Protein RefSeq | NP_001324 |
| mRNA RefSeq | NM_001333.3 |