Description / anti-mouse Cathepsin H monoclonal antibody
Cathepsin H is a lysosomal cysteine protease of the papain family (. It is synthesized as a precursor protein, consisting of a signal peptide (residues 1-20), a propeptide (residues 21-95), a mini chain (residues 96-103), a heavy chain (residues 114-290) and a light chain (residues 291-333). A truncated form with a 12 amino acid deletion in the signal peptide region is secreted. Cathepsin H is the only known monoaminopeptidase in the papain family. Cathepsin H expression is significantly increased in prostate tumors, sera of asthmatic patients, and mucosa of colorectal cancer patients.
More Information
| Size | 100 µg |
|---|---|
| Source | Rat |
| Isotype | IgG2 |
| Clone Nr. | (#8J11) |
| Species Reactivity | Mouse |
| Formulation | lyophilized |
| Buffer | PBS |
| Reconstitution | Centrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml. |
| Stability and Storage | Lyophilized samples are stable for 2 years from date of receipt when stored at -70°C. Reconstituted antibody can be aliquoted and stored frozen at < -20°C for at least six months without detectable loss of activity. |
| Preparation | This antibody was produced from a hybridoma (mouse myeloma fused with spleen cells from a rat) immunized with mouse recombinant protein of Cathepsin-H. |
| Antigen | recombinant human Cathepsin-H |
| Application | WB |
| Synonyms | Ctsh; AL022844 |
| Uniprot ID | P49935 |
| Protein RefSeq | NP_031827 |
| mRNA RefSeq | NM_007801 |