Betacellulin Human 20 µg

In stock

Cat-Nr.
100-332
Size
20 µg
  €221.00

Description / Betacellulin

Betacellulin is an EGF-related polypeptide growth factor that signals through the EGF receptor. It is produced in several tissues, including the pancreas, small intestine, and in certain tumor cells. Betacellulin is a potent mitogen for retinal pigment epithelial cells and vascular smooth muscle cells. Human Betacellulin is initially synthesized as a glycosylated 32.0 kDa transmembrane precursor protein, which is processed by proteolytic cleavage to produce the mature sequence. Recombinant human Betacellulin is a 9.0 kDa monomeric protein, containing 80 amino residues, which comprises the mature EGF homologous portion of the Betacellulin protein.

More Information

Size 20 µg
Source E. coli
Biological Activity The ED50 was determined by the dose-dependent stimulation of the proliferation of murine Balb/3T3 cells is ≤ 0.05 ng/ml, corresponding to a specific activity of ≥ 2 x 107 units/mg.
Purity Confirmation >98% by SDS-PAGE & HPLC analyses
Length [aa] 80
Molecular Weight 9.0 kDa
Species Reactivity Mouse, Human
Formulation lyophilized
Protein Sequence DGNSTRSPET NGLLCGDPEE NCAATTTQSK RKGHFSRCPK QYKHYCIKGR CRFVVAEQTP SCVCDEGYIG ARCERVDLFY
Synonyms BTC
Uniprot ID P35070
Protein RefSeq NP_001720
mRNA RefSeq NM_001729

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