BD-2 (SAP1) Mouse 20 µg

In stock

Cat-Nr.
M10-008
Size
20 µg
  €221.00

Description / BD-2 (SAP1)

Defensins (alpha and beta) are cationic peptides with a broad spectrum of antimicrobial activity that comprise an important arm of the innate immune system. The α-defensins are distinguished from the β-defensins by the pairing of their three disulfide bonds. To date, six human β-defensins have been identified; BD-1, BD-2, BD-3, BD-4, BD-5 and BD-6. β-defensins are expressed on some leukocytes and at epithelial surfaces. In addition to their direct antimicrobial activities, they can act as chemoattractants towards immature dendritic cells and memory T cells. The β-defensin proteins are expressed as the C-terminal portion of precursors, and are released by proteolytic cleavage of a signal sequence and, in some cases, a propeptide sequence. β-defensins contain a six-cysteine motif that forms three intra-molecular disulfide bonds. Recombinant Murine BD-2 is a 5.5 kDa protein containing 51 amino acid residues.

More Information

Size 20 µg
Source E. coli
Biological Activity Not available.
Purity Confirmation > 98% by SDS-PAGE & HPLC analyses
Length [aa] 51
Molecular Weight 5.5 kDa
Species Reactivity Mouse
Formulation lyophilized
Protein Sequence AVGSLKSIGY EAELDHCHTN GGYCVRAICP PSARRPGSCF PEKNPCCKYM K
Synonyms Beta-Defensin 2, DEFB2, DEFB4A, Skin-Antimicrobial Peptide 1, SAP1
Uniprot ID P82020
Protein RefSeq NP_034160.1
mRNA RefSeq NM_010030.1

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