Description / human BCMA protein
BCMA, a member of the TNF receptor superfamily, binds to BAFF and APRIL. BCMA is expressed on mature B-cells and other B-cell lines and plays an important role in B cell development, function and regulation. BCMA also has the capability to activate NF-kappaB and JNK. The human BCMA gene codes for a 184 amino acid type I transmembrane protein, which contains a 54 amino acid extracellular domain, a 23 amino acid transmembrane domain, and a 107 amino acid extracellular domain. Recombinant soluble BCMA is a 50 amino acid polypeptide (5.3 kDa) comprising the TNFR homologous region of the BCMA protein.
More Information
| Size | 250 µg |
|---|---|
| Source | E. coli |
| Biological Activity | Data not available. |
| Purity Confirmation | > 98% by SDS-PAGE & HPLC analyses |
| Length [aa] | 50 |
| Molecular Weight | 5.3 kDa |
| Species Reactivity | Human |
| Formulation | lyophilized |
| Protein Sequence | AGQCSQNEYF DSLLHACIPC QLRCSSNTPP LTCQRYCNAS VTNSVKGTNA |
| Synonyms | TNFRSF17; BCM; BCMA; CD269 |
| Uniprot ID | Q02223 |
| Protein RefSeq | NP_001183 |
| mRNA RefSeq | NM_001192 |