Description / mouse BCA-1 protein
BCA-1/BLC, a CXC chemokine, is expressed in the liver, spleen, lymph nodes, appendix and stomach. It exerts its activities through its only receptor CXCR5. BCA-1/BLC is a potent chemoattractant for B lymphocytes and induces weak chemotactic response in T cells and macrophages. It manifests no activity on neutrophils and monocytes. Recombinant murine BLC is a 9.8 kDa protein containing 88 amino acid residues including the four highly conserved cysteine residues present in CXC chemokines.
More Information
| Size | 1000 µg |
|---|---|
| Source | E. coli |
| Biological Activity | Determined by its ability to chemoattract human B cells using a concentration range of 1.0-10.0 ng/ml. |
| Purity Confirmation | > 98% by SDS-PAGE & HPLC analyses |
| Length [aa] | 87 |
| Molecular Weight | 10.3 kDa |
| Species Reactivity | Human, Mouse, Leech, Bacteria |
| Formulation | lyophilized |
| Protein Sequence | VLEVYYTSLR CRCVQESSVF IPRRFIDRIQ ILPRGNGCPR KEIIVWKKNK SIVCVDPQAE WIQRMMEVLR KRSSSTLPVP VFKRKIP |
| Synonyms | Cxcl13; BLC; Angie; BCA-1; BLR1L; ANGIE2; Scyb13; 4631412M08Rik |
| Uniprot ID | O55038 |
| Protein RefSeq | NP_061354.1 |
| mRNA RefSeq | NM_018866.2 |