Description / BCA-1
BCA-1/BLC, a CXC chemokine, is expressed in the liver, spleen, lymph nodes, appendix and stomach. It exerts its activities through its only receptor CXCR5. BCA-1/BLC is a potent chemoattractant for B lymphocytes and induces weak chemotactic response in T cells and macrophages. It manifests no activity on neutrophils and monocytes. Recombinant Human BCA-1 is a 10.3 kDa protein containing 87 amino acid residues including the four highly conserved cysteine residues present in CXC chemokines.
More Information
Size | 20 µg |
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Source | E. coli |
Biological Activity | The biological activity of human BCA-1 was determined by chemotaxis assay using human B cells. Significant chemotaxis was achieved at a concentration range of 1.0-10 ng/ml. |
Purity Confirmation | > 98% by SDS-PAGE & HPLC analyses |
Length [aa] | 87 |
Molecular Weight | 10.3 kDa |
Species Reactivity | Human |
Formulation | lyophilized |
Protein Sequence | VLEVYYTSLR CRCVQESSVF IPRRFIDRIQ ILPRGNGCPR KEIIVWKKNK SIVCVDPQAE WIQRMMEVLR KRSSSTLPVP VFKRKIP |
Synonyms | CXCL13; BLC; BCA1; ANGIE; BCA-1; BLR1L; ANGIE2; SCYB13 |
Uniprot ID | O43927 |
Protein RefSeq | NP_006410.1 |
mRNA RefSeq | NM_006419.2 |