BAFF receptor, soluble Human 10 µg

In stock

Cat-Nr.
S01-038S
Size
10 µg
  €112.00

Description / BAFF receptor, soluble

BAFF Receptor (BAFF-R), a member of the TNFR superfamily, is highly expressed in spleen, lymph node, and resting B cells and to some extent in activated B cells, resting CD4+ cells and peripheral blood leukocytes. BAFF-R is a type III transmembrane protein that binds with high specificity to BAFF (TNFSF13B). BAFF-R/BAFF signaling plays a critical role in B cell survival and maturation. Recombinant human BAFF-R is a 76 amino acid polypeptide (7.7 kDa) corresponding to the extracellular portion of the full BAFF-R protein.

More Information

Size 10 µg
Source E. coli
Biological Activity Determined by its ability to block BAFF induced mouse splenocyte survival. The expected ED50 for this effect is 2.0-4.0 μg/ml in the presence of 1.0 μg/ml of human soluble BAFF.
Purity Confirmation > 95% by SDS-PAGE & HPLC analyses
Length [aa] 76
Molecular Weight 7.7 kDa
Species Reactivity Mouse
Formulation lyophilized
Protein Sequence MRRGPRSLRG RDAPAPTPCV PAECFDLLVR HCVACGLLRT PRPKPAGASS PAPRTALQPQ ESVGAGAGEA ALPLPG
Synonyms TNFRSF13C; BAFFR; CD268; CVID4; BAFF-R; BROMIX; prolixin
Uniprot ID Q96RJ3
Protein RefSeq NP_443177
mRNA RefSeq NM_052945

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