Description / Anti-Human AMIGO2 monoclonal antibody
Adhesion of cancer cells to vascular endothelial cells in target organs is an initial step in cancer metastasis. Previous studies revealed that Amphoterin-induced gene and open reading frame 2 (AMIGO2) promotes the adhesion of tumor cells to liver endothelial cells, followed by the formation of liver metastasis in a mouse model. However, the precise mechanism underlying AMIGO2-promoted the adhesion of tumor cells and liver endothelial cells remains unknown.
More Information
| Size | 50 µg |
|---|---|
| Source | Mouse |
| Isotype | IgG2 |
| Clone Nr. | (#4D27) |
| Species Reactivity | Human |
| Formulation | lyophilized |
| Buffer | PBS |
| Reconstitution | Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml. |
| Stability and Storage | Lyophilized samples are stable for 2 years from date of receipt when stored at -70°C. Reconstituted antibody can be aliquoted and stored frozen at < -20 °C for at least for six months without detectable loss of activity. |
| Antigen | Recombinant hu AMIGO2 |
| Application | WB |
| Synonyms | Amphoterin-induced protein 2, Alivin-1, Differentially expressed in gastric adenocarcinomas (DEGA) |
| Uniprot ID | Q86SJ2 |
| Protein RefSeq | NP_001137140.1 |
| mRNA RefSeq | NM_001143668.1 |