AITRL Human 20 µg

In stock

Cat-Nr.
100-122
Size
20 µg
  €204.00

Description / AITRL

AITRL, a member of the TNF superfamily, is expressed in endothelial cells, and signals through the AITR receptor. AITRL regulates T-cell proliferation and survival, and effectuates the interaction between T lymphocytes and endothelial cells. The AITRL gene codes for a type II transmembrane protein comprised of 177 amino acids, including a 28 amino acid cytoplasmic region, a 21 amino acid transmembrane domain and a 128 amino acid extracellular domain. Recombinant human soluble AITRL is a 14.3 kDa protein, containing 126 amino acid residues corresponding to the extracellular domain of AITRL.

More Information

Size 20 µg
Source E. coli
Biological Activity Determined by its ability to stimulate IL-8 production by human PBMC using a concentration range of 1.0-10.0 ng/ml. Please Note: Results may vary with PBMC donors.
Purity Confirmation > 97% by SDS-PAGE & HPLC analyses
Length [aa] 126
Molecular Weight 14.3 kDa
Species Reactivity Human
Formulation lyophilized
Protein Sequence ETAKEPCMAKFGPLPSKWQMASSEPPCVNKVSDWKLEILQNGLYLIYGQVAPNANYNDVAPFEVRLYKNKDMIQTLTNKSKIQNVGGTYELHVGDTIDLIFNSEHQVLKNNTYWGIILLANPQFI
Synonyms TNFSF18; TL6; AITRL; GITRL; hGITRL
Uniprot ID Q9UNG2
Protein RefSeq NP_005083.2
mRNA RefSeq NM_005092.3

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