Activin-A Human 2 µg

In stock

Cat-Nr.
100-012S
Size
2 µg
  €112.00

Description / Activin-A

Activin A is a TGF-beta family member that exhibits a wide range of biological activities including regulation of cellular proliferation and differentiation, and promotion of neuronal survival. Elevated levels of Activin A in human colorectal tumors and in post-menopausal woman have been implicated in colorectal and breast cancers, respectively. The biological activities of Activin A can be neutralized by inhibins and by the diffusible TGF-beta antagonist, Follistatin. Human Activin A is a 26 kDa disulfide-linked homodimer of two beta A chains, each containing 116 amino acid residues.

More Information

Size 2 µg
Source CHO cells
Biological Activity Determined by its ability to inhibit the proliferation of mouse MPC-11 cells. The expected ED50 is ≤ 2.0 ng/ml, corresponding to a specific activity of ≥ 5 x 105 units/mg.
Purity Confirmation > 95% by SDS-PAGE & HPLC analyses
Length [aa] 116
Molecular Weight 26.0 kDa
Species Reactivity Human, Mouse, Rat
Formulation lyophilized
Protein Sequence GLECDGKVNICCKKQFFVSFKDIGWNDWIIAPSGYHANYCEGECPSHIAGTSGSSLSFHSTVINHYRMRGHSPFANLKSCCVPTKLRPMSMLYYDDGQNIIKKDIQNMIVEECGCS
Synonyms Inhibin beta-1, FRP, FSH (Follicle-stimulating hormone)-releasing protein
Uniprot ID P08476
Protein RefSeq NP_002183.1
mRNA RefSeq NM_002192.2
Adult stem cells-derived organoids Lung
Pluripotent stem cells-derived organoids Esophagus, Intestine, Liver, Lung, Pancreas, Stomach

Compatible products

Navigating through the elements of the carousel is possible using the tab key. You can skip the carousel or go straight to carousel navigation using the skip links.
SKU: 101-M202
€533.00

In stock

All prices plus VAT + possible delivery charges