Description / Anti-Human ABCG2 (CD338) monoclonal antibody
ABCG2 is one of at least three human ATP binding cassette (ABC) transporters which can facilitate the export from cells of a wide range of chemically unrelated drug molecules. This capacity for multidrug transport is not only a confounding factor in chemotherapy, but is also one of the more perplexing phenomena in transporter biochemistry.
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| Size | 50 µg |
|---|---|
| Source | Mouse |
| Isotype | IgG2 |
| Clone Nr. | (#2J39) |
| Species Reactivity | Human |
| Formulation | lyophilized |
| Buffer | PBS |
| Reconstitution | Centrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml. |
| Stability and Storage | Lyophilized samples are stable for 2 years from date of receipt when stored at -70°C. Reconstituted antibody can be aliquoted and stored frozen at < -20 °C for at least for six months without detectable loss of activity. |
| Antigen | human recombinant ABCG2 protein |
| Application | IHC (F/P), FC |
| Synonyms | ATP-binding cassette sub-family G member 2, Breast cancer resistance protein |
| Uniprot ID | Q9UNQ0 |
| Protein RefSeq | NP_004818.2 |
| mRNA RefSeq | NM_004827.2 |