Human GDF-10

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Cat-Nr.100-390
Size20 µg
Price180 €
SourceE. coli
Formulationliquid
Purity Confirmation> 95% by SDS-PAGE
Length [aa]111
Molecular Weight12.5 Kd
Biological ActivityData not available.
Species ReactivityHuman
SynonymsGDF10; BMP3B; BMP-3b
DescriptionGDF-10 is a member of the BMP family and the TGF-beta superfamily. GDF-10 is expressed in femur, brain, lung, skeletal, muscle, pancreas and testis, and has a role in head formation and possibly multiple roles in skeletal morphogenesis. In humans, GDF-10 mRNA is found in the cochlea and lung of fetuses, and in testis, retina, pineal gland, and other neural tissues of adults. The BMP family members are regulators of cell growth and differentiation in both embryonic and adult tissues. These proteins are characterized by a polybasic proteolytic processing site which is cleaved to produce a mature protein containing 7 conserved cysteine residues. GDF-10 produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 111 amino acids (369-478 a.a.) and having a total molecular mass of 12.5 kDa.
Protein SequenceMQWDEPRVCS RRYLKVDFAD IGWNEWIISP KSFDAYYCAG ACEFPMPKIV RPSNHATIQS IVRAVGIIPG IPEPCCVPDK MNSLGVLFLD ENRNVVLKVY PNMSVDTCAC R
Uniprot IDP55107
Protein RefSeqNP_004953.1
mRNA RefSeqNM_004962

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