Human c-reactive protein (CRP)

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Cat-Nr.100-144
Size1000 µg
Price350 €
SourceE. coli
Formulationliquid
Purity Confirmation> 95% by SDS-PAGE & HPLC analyses
Length [aa]205
Molecular Weight115 kDa (Pentamer)
Biological ActivityData not available.
Species ReactivityHuman
Buffer20mM Tris (pH 7.5), 2mM CaCl2, 1.4M NaCl, 0.05% NaN3
Stability and StorageThe liquid CRP should be stored at all times at 4°C.
SynonymsC-reactive protein, CRP, PTX1, MGC88244, MGC149895.
DescriptionCRP is an acute phase protein that correlates with inflammatory disease and is synthesized by hepatocytes during the acute phase response by certain cytokines (IL-1 and TNF Alpha and Beta). CRP levels increase dramatically (up to 1,000 fold) and serve as a useful marker of inflammation in such conditions as bacterial infection, rheumatoid arthritis, viral infections, transplantation rejection, meningitis, myocardial infarction, septicemia, osteomyelitis and others. CRP is also highly correlated to Serum Amyloid A levels.
Protein SequenceQTDMSRKAFVFPKESDTSYVSLKAPLTKPLKAFTVCLHFYTELSSTRGYSIFSYATKRQDNEILIFWSKDIGYSFTVGGSEILFEVPEVTVAPVHICTSWESASGIVEFWVDGKPRVRKSLKKGYTVGAEASIILGQEQDSFGGNFEGSQSLVGDIGNVNMWDFVLSPDEINTIYLGGPFSPNVLNWRALKYEVQGEVFTKPQLW
Uniprot IDP02741
Protein RefSeqNP_000558
mRNA RefSeqNM_000567.2

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