Mouse FGF-21

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Cat-Nr.M10-047S
Size5 µg
Price75 €
CategoryCytokines & Growth Factors
SourceE. coli
Species ReactivityMouse
Formulationlyophilized
Purity Confirmation≥ 95% by SDS-PAGE gel and HPLC analyses
Length [aa]182
Molecular Weight20.1 kDa
SynonymsFibroblast Growth Factor-21, FGFL
DescriptionFGF-21 is a secreted growth factor that is a member of the FGF family. Proteins of this family play a central role during prenatal development, postnatal growth and regeneration of a variety of tissues, by promoting cellular proliferation and differentiation. FGF-21, in the presence of β-Klotho as a protein cofactor, signals through the FGFR 1c and 4 receptors, and stimulates insulin-independent glucose uptake by adipocytes. Recombinant Murine FGF-21 is a 20.1 kDa protein containing 182 amino acid residues.
Protein SequenceMAYPIPDSSP LLQFGGQVRQ RYLYTDDDQD TEAHLEIRED GTVVGAAHRS PESLLELKAL KPGVIQILGV KASRFLCQQP DGALYGSPHF DPEACSFREL LLEDGYNVYQ SEAHGLPLRL PQKDSPNQDA TSWGPVRFLP MPGLLHEPQD QAGFLPPEPP DVGSSDPLSM VEPLQGRSPS YAS
Uniprot IDQ9JJN1
Protein RefSeqNP_064397.1
mRNA RefSeqNM_020013.4

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