Mouse Amphiregulin

Slide this table

Cat-Nr.M10-019S
Size10 µg
Price75 €
CategoryCytokines & Growth Factors
SourceE. coli
Species ReactivityMouse
Formulationlyophilized
Purity Confirmation≥ 95% by SDS-PAGE gel and HPLC analyses
Length [aa]98
Molecular Weight11.3 kDa
SynonymsAR, AREG, Colorectum cell-derived growth factor (CRDGF)
DescriptionAmphiregulin is an EGF-related growth factor that signals through the EGF/TGF-α receptor, and stimulates growth of keratinocytes, epithelial cells and some fibroblasts. Amphiregulin also inhibits the growth of certain carcinoma cell lines. Synthesized as a transmembrane protein, Amphiregulin’s extracellular domain is proteolytically processed to release the mature protein. There are 6 conserved cysteine residues, which form 3 intramolecular disulfide bonds essential for biological activity. Recombinant Murine Amphiregulin is an 11.3 kDa glycoprotein consisting of 98 amino acid residues.
Protein SequenceSVRVEQVIKP KKNKTEGEKS TEKPKRKKKG GKNGKGRRNK KKKNPCTAKF QNFCIHGECR YIENLEVVTC NCHQDYFGER CGEKSMKTHS EDDKDLSK
Uniprot IDP31955
Protein RefSeqNP_033834.1
mRNA RefSeqNM_009704.4

All prices plus VAT + possible delivery charges