Ovine Leptin antagonist (mutant L39A/D40A/F41A/I42A)

Slide this table

Cat-Nr.500-067S
Size50 µg
Price175 €
CategoryCytokines & Growth Factors
SourceE. coli
Species ReactivityOvine
Formulationlyophilized
Purity Confirmation> 98.0% as determined by Gel filtration and SDS-PAGE gel.
Length [aa]146
Molecular Weight16.0 kDa
N Terminal SequenceAVPIR
ReconstitutionIt is recommended to reconstitute the lyophilized ovine recombinant leptin antagonist in sterile 0.4% NaHCO3 adjusted, not less than 100µg/ml, which can then be further diluted to other aqueous solutions.
SynonymsLep; ob; obese
DescriptionRecombinant ovine leptin, one polypeptide chain containing 146 amino and additional Ala at N-terminus acids and having a molecular mass of ~ 16 kDa, ovine leptin was mutated, resulting in L39A/D40A/F41A/I42A mutant was purified by proprietary chromatographic techniques. Preparation of leptin antagonists was published - Niv-Spector et al, Biochem. J 291;221-230 (2005).
Protein SequenceAVPIRKVQDDTKTLIKTIVTRINDISHTQSVSSKQRVTGAAAAPGLHPLLSLSKMDQTLAIYQQILASLPSRNVIQISNDLENLRDLLHLLAASKSCPLPQVRALESLESLGVVLEASLYSTEVVALSRLQGSLQDMLRQLDLSPG
Protein RefSeqXP_027824581.2
mRNA RefSeqXM_027968780.2

All prices plus VAT + possible delivery charges