Rabbit Anti-Mouse VEGF-A

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Cat-Nr.103-PA03
Size200 µg
Price250 €
CategoryPolyclonal Antibody
Clone Nr.Rabbit IG
Species ReactivityMouse
Formulationlyophilized
BufferPBS
ReconstitutionReconstitute in sterile water to a concentration of 0.1-1.0mg/mL.
Stability and StorageThe lyophilized antibody is stable at room temperature for up to 1 month. The reconstituted antibody is stable for at least two weeks at 2-8 °C. Frozen aliquots are stable for at least 6 months when stored at -20 °C.
PreparationProduced from sera of rabbits immunized with highly pure recombinant murine VEGF164. Anti-murine VEGF-A was purified by affinity chromatography with immobilized Protein A.
AntigenRecombinant mouse VEGF164 (RT #M30-001)
ApplicationWB, IHC (P), E
SynonymsVegfa; Vpf; Vegf; Vegf120; Vegf164; Vegf188
DescriptionMouse VEGF is a potent growth and angiogenic cytokine. It stimulates proliferation and survival of endothelial cells, and promotes angiogenesis and vascular permeability. Expressed in vascularized tissues, VEGF plays a prominent role in normal and pathological angiogenesis. Substantial evidence implicates VEGF in the induction of tumor metastasis and intra-ocular neovascular syndromes. VEGF signals through the three receptors; fms-like tyrosine kinase (flt-1), KDR gene product (the murine homolog of KDR is the flk-1 gene product) and the flt4 gene product. Recombinant murine VEGF (isoform 164) is a 39.0 kDa disulfide-linked homodimeric protein consisting of two 164 amino acid polypeptide chains.
Uniprot IDQ00731
Protein RefSeqNP_001020421
mRNA RefSeqNM_001025250

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