Rabbit Anti-Human IL-31

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Cat-Nr.102-P237
Size100 µg
Price235 €
CategoryPolyclonal Antibody
Clone Nr.Rabbit IgG
Species ReactivityHuman
Formulationlyophilized from PBS
BufferPBS
ReconstitutionReconstitute in sterile water to a concentration of 0.1-1.0mg/mL.
Stability and StorageThe lyophilized antibody is stable for at least 2 years from date of receipt at -20°C. The reconstituted antibody is stable for at least two weeks at 2-8°C. Frozen aliquots are stable for at least 6 months when stored at -20°C.
PreparationProduced from sera of rabbits pre-immunized with highly pure (>98%) recombinant human IL-31. Anti-Human IL-31 specific antibody was purified by affinity chromatography employing immobilized human IL-31 matrix.
AntigenRecombinant human IL-31
ApplicationELISA, WB
SynonymsIL31; IL-31
DescriptionInterleukin 31 (IL-31) is a secreted, T-cell-derived, 24- kDa, short-chain member of the alpha-helical family of cytokines. The mature region is 141 amino acids (aa) in length and exhibits four alpha-helices. Human and mouse IL-31 are highly divergent at 24% aa sequence identity. The receptor for IL-31 is found on keratinocytes and monocytes. It is a heterodimer composed of the Oncostatin M receptor and a novel gp130-related molecule. IL-31 may be involved in pruritis, or skin itching.
Uniprot IDQ6EBC2
Protein RefSeqNP_001014358.1
mRNA RefSeqNM_001014336.1

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