Mouse Anti-Human IL-18 receptor alpha

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Cat-Nr.101-M493
Size100 µg
Price250 €
CategoryMonoclonal Antibody
Clone Nr.(#8H22)
IsotypeIgG1
Species ReactivityHuman
Formulationlyophilized
BufferPBS
ReconstitutionReconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.
Stability and StorageLyophilized samples are stable for 2 years from date of receipt when stored at -70°C. Reconstituted antibody can be aliquoted and stored frozen at < -20 °C for at least for six months without detectable loss of activity.
PreparationThis antibody was produced from a hybridoma (mouse myeloma fused with spleen cells from a mouse) immunized with human recombinant protein of IL-18 Ra extracellular domain.
Antigenrecombinant human IL-18 R beta EC domain
ApplicationWB
SynonymsIL18RAP; ACPL; CD218b; IL18RB; CDw218b; IL-18 receptor
DescriptionHuman IL-18 R cDNA encodes a 541 amino acid (aa) precursor type I membrane protein with a hydrophobic signal, an extracellular domain comprised of three immunoglobulin-like domains, a transmembrane domain and a cytoplasmic region of approximately 200 aa residues. Human and mouse IL-18 R share 65% amino acid sequence homology. IL-18 R is widely expressed in numerous tissues including spleen, thymus, leukocyte, liver, lung, heart, small and large intestine, prostate and placenta
Uniprot IDQ13478
Protein RefSeqNP_003846.1
mRNA RefSeqNM_003855.3

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