Rat Anti-Mouse uPAR

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Cat-Nr.103-M284
Size100 µg
Price250 €
CategoryMonoclonal Antibody
Clone Nr.(#7J34)
IsotypeIgG2
Species ReactivityMouse
Formulationlyophilized
BufferPBS
ReconstitutionReconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.
Stability and StorageLyophilized samples are stable for 2 years from date of receipt when stored at -70°C. Reconstituted antibody can be aliquoted and stored frozen at < -20 °C for at least for six months without detectable loss of activity.
PreparationThis antibody was produced from a hybridoma (mouse myeloma fused with spleen cells from a rat immunized with purified mouse recombinant uPAR. The IgG2 fraction of the culture supernatant was purified by Protein A/G affinity chromatography.
AntigenMouse recombinant protein of uPAR
ApplicationWB
SynonymsPlaur; Cd87; uPAR; u-PAR
DescriptionThe urokinase-type plasminogen activator (uPA) is one of two activators that converts plasminogen to plasmin. uPA binds with high-affinity to the cell surface via the GPI-linked receptor uPAR, which serves to localize uPA proteolytic activity. Human uPAR cDNA encodes a 335 amino acid (aa) precursor protein with a 22 aa signal peptide, five potential N-linked glycosylation sites and a C-terminal GPI-anchor site.
Uniprot IDP35456
Protein RefSeqNP_035243.1
mRNA RefSeqNM_011113.3

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