Rat Anti-Mouse TNFSF6

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Cat-Nr.103-M495
Size100 µg
Price250 €
CategoryMonoclonal Antibody
Clone Nr.(#8K41)
IsotypeIgG2
Species ReactivityMouse
Formulationlyophilized
BufferPBS
ReconstitutionReconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.
Stability and StorageLyophilized samples are stable for 2 years from date of receipt when stored at -70°C. Reconstituted antibody can be aliquoted and stored frozen at < -20 °C for at least for six months without detectable loss of activity.
PreparationThis antibody was produced from a hybridoma (mouse myeloma fused with spleen cells from a rat) immunized with mouse recombinant protein of TNFSF6.
AntigenRecombinant mouse TNFSF6
ApplicationWB
SynonymsFasl; gld; CD178; CD95L; Fas-L; Faslg; CD95-L; Tnfsf6; APT1LG1
DescriptionFas Ligand is a 40 kDa type II transmembrane protein belonging to the TNF superfamily. The specific receptor for Fas Ligand is Fas (CD95, Apo-1). Fas Ligand is predominantly expressed on activated T cells and natural killer cells, while Fas is expressed on various types of cells. The Fas/Fas Ligand system plays a crucial role in modulating immune responses by inducing cell specific apoptosis. Human Fas Ligand shares 81% sequence identity with mouse Fas Ligand and 78% sequence identity with rat Fas Ligand.
Uniprot IDP41047
Protein RefSeqNP_034307.1
mRNA RefSeqNM_010177.4

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