Mouse Anti-Human TNFSF6

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Cat-Nr.101-M683
Size100 µg
Price250 €
CategoryMonoclonal Antibody
Clone Nr.(#1Z20)
IsotypeIgG1
Species ReactivityHuman
Formulationlyophilized
BufferPBS
ReconstitutionReconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.
Stability and StorageLyophilized samples are stable for 2 years from date of receipt when stored at -70°C. Reconstituted antibody can be aliquoted and stored frozen at < -20 °C for at least for six months without detectable loss of activity.
PreparationThis antibody was produced from a hybridoma (mouse myeloma fused with spleen cells from a mouse) immunized with human recombinant TNFSF6 extracellular domain (also called Fas-ligand).
Antigenrecombinant human TNFSF6 EC domain
ApplicationWB
SynonymsFASLG; FASL; CD178; CD95L; CD95-L; TNFSF6; APT1LG1
DescriptionFas Ligand is a 40 kDa type II transmembrane protein belonging to the TNF superfamily. The specific receptor for Fas Ligand is Fas (CD95, Apo-1). Fas Ligand is predominantly expressed on activated T cells and natural killer cells, while Fas is expressed on various types of cells. The Fas/Fas Ligand system plays a crucial role in modulating immune responses by inducing cell specific apoptosis. Human Fas Ligand shares 81% sequence identity with mouse Fas Ligand and 78% sequence identity with rat Fas Ligand.
Uniprot IDP48023
Protein RefSeqNP_000630.1
mRNA RefSeqNM_000639.1

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