Mouse Anti-Human TNFSF18

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Cat-Nr.101-M677
Size100 µg
Price250 €
CategoryMonoclonal Antibody
Clone Nr.(#4Q25)
IsotypeIgG1
Species ReactivityHuman
Formulationlyophilized
BufferPBS
ReconstitutionReconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.
Stability and StorageLyophilized samples are stable for 2 years from date of receipt when stored at -70°C. Reconstituted antibody can be aliquoted and stored frozen at < -20 °C for at least for six months without detectable loss of activity.
PreparationThis antibody was produced from a hybridoma (mouse myeloma fused with spleen cells from a mouse) immunized with human recombinant protein of TNFSF18 extracellular domain (also called GITR ligand).
AntigenHuman recombinant TNFSF18 EC domain
ApplicationFC, N
SynonymsTNFSF18; TL6; AITRL; GITRL; hGITRL
DescriptionGITR Ligand (GITRL) is a member of the TNF superfamily and has been designated TNFSF18. The carboxy-terminal extracellular domain shows sequence similarily to TNF-alpha/TNFSF1A, Fas Ligand/TNFSF6, TRAIL/TNFSF10, and TNF-beta/TNFSF1B. GITRL is constitutively expressed in human umbilical vein endothelial cells but is not expressed in resting or stimulated T cell lines, B cell lines or peripheral blood mononuclear cells.
Uniprot IDQ9UNG2
Protein RefSeqNP_005083.2
mRNA RefSeqNM_005092.3

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