Rat Anti-Human TNFRSF17

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Cat-Nr.101-M658
Size100 µg
Price250 €
CategoryMonoclonal Antibody
Clone Nr.(#3D44)
IsotypeIgG2
Species ReactivityHuman
Formulationlyophilized
BufferPBS
ReconstitutionReconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.
Stability and StorageLyophilized samples are stable for 2 years from date of receipt when stored at -70°C. Reconstituted antibody can be aliquoted and stored frozen at < -20 °C for at least for six months without detectable loss of activity.
PreparationThis antibody was produced from a hybridoma (mouse myeloma fused with spleen cells from a mouse) immunized with human recombinant protein of the extracellular domain of TNFRSF17 (BCMA).
Antigenrecombinant human TNFRSF17 EC domain
ApplicationWB, Blocking
SynonymsTNFRSF17; BCM; BCMA; CD269
DescriptionB cell maturation protein (BCMA) is a member of the TNF receptor superfamily (TNFRSF17). BCMA is expressed in immune organs and mature B cell lines. Although some expression has been observed at the cell surface, BCMA appears to be localized to the Golgi compartment. BCMA binding to APRIL or BAFF stimulates IgM production in peripheral blood B cells and increases the survival of cultured B cells. Mature human and mouse BCMA share 86% amino acid sequence identity.
Uniprot IDQ02223
Protein RefSeqNP_001183.2
mRNA RefSeqNM_001192.2

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