Rat Anti-Mouse Sclerostin

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Cat-Nr.103-M270
Size100 µg
Price250 €
CategoryMonoclonal Antibody
Clone Nr.(#4D77)
IsotypeIgG2
Species ReactivityMouse
Formulationlyophilized
BufferPBS
ReconstitutionReconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.
Stability and StorageLyophilized samples are stable for 2 years from date of receipt when stored at -70°C. Reconstituted antibody can be aliquoted and stored frozen at < -20 °C for at least for six months without detectable loss of activity.
PreparationThis antibody was produced from a hybridoma (mouse myeloma fused with spleen cells from a rat immunized with purified mouse recombinant Sclerostin. The IgG2 fraction of the culture supernatant was purified by Protein A/G affinity chromatography.
Antigenmouse recombinant protein of Sclerostin
ApplicationWB
SynonymsSost; 5430411E23Rik
DescriptionSOST, also known as sclerostin, is a member of the Cerberus/DAN family of BMP antagonists, a group of secreted glycoproteins characterized by a cysteine-knot motif. SOST is expressed by osteoclasts in developing bones of mouse embryos, including both intramembranously forming skull bones and endochondrally forming long bones.
Uniprot IDQ99P68
Protein RefSeqNP_077769.3
mRNA RefSeqNM_024449.5

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