Mouse Anti-Human SCF-R

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Cat-Nr.101-M622
Size100 µg
Price250 €
CategoryMonoclonal Antibody
Clone Nr.(#14G5)
IsotypeIgG1
Species ReactivityHuman
Formulationlyophilized
BufferPBS
ReconstitutionReconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.
Stability and StorageLyophilized samples are stable for 2 years from date of receipt when stored at -70°C. Reconstituted antibody can be aliquoted and stored frozen at < -20 °C for at least for six months without detectable loss of activity.
PreparationThis antibody was produced from a hybridoma (mouse myeloma fused with spleen cells from a mouse immunized with human recombinant protein of SCF-R extracellular domain (also called c-kit).
Antigenrecombinant human SCF-R EC domain
ApplicationWB, N
SynonymsKIT, PBT; SCFR; C-Kit; CD117
DescriptionStem cell factor receptor (CD117, the gene product of the c-kit proto-oncogene) and its ligand, stem cell factor, play essential roles in gametogenesis, melanogenesis and hematopoiesis. Stem cell factor receptor is a member of the type III subfamily of receptor tyrosine kinases (RTK) that also includes the receptors for M-CSF, Flt-3 and PDGF. It is expressed in hematopoietic progenitor cells, normal B and T cell progenitor cells, mast cells, germ cells, melanocytes, neurons, glial cells, placenta, kidney, lung and gut.
Uniprot IDP10721
Protein RefSeqNP_000213.1
mRNA RefSeqNM_000222.2

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